Barbara Filipek Selected Research

pyrrolidine-2,5-dione

2/2020	Analgesic and antiallodynic activity of novel anticonvulsant agents derived from 3-benzhydryl-pyrrolidine-2,5-dione in mouse models of nociceptive and neuropathic pain.
1/2018	Evaluation of anticonvulsant and analgesic activity of new hybrid compounds derived from N-phenyl-2-(2,5-dioxopyrrolidin-1-yl)-propanamides and -butanamides.
3/2016	Evaluation of anticonvulsant and antinociceptive properties of new N-Mannich bases derived from pyrrolidine-2,5-dione and 3-methylpyrrolidine-2,5-dione.

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Barbara Filipek Research Topics

Disease

17	Pain (Aches) 10/2021 - 09/2009
15	Cardiac Arrhythmias (Arrythmia) 01/2016 - 12/2004
13	Seizures (Absence Seizure) 01/2018 - 08/2014
11	Neuralgia (Stump Neuralgia) 10/2021 - 07/2014
8	Hyperalgesia 01/2020 - 01/2004
6	Epilepsy (Aura) 10/2021 - 03/2016
5	Peripheral Nervous System Diseases (PNS Diseases) 11/2020 - 07/2014
5	Acute Pain 02/2018 - 01/2012
4	Inflammation (Inflammations) 01/2019 - 01/2013
3	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 05/2015
3	Hypertension (High Blood Pressure) 01/2019 - 01/2016
3	Diabetic Neuropathies (Diabetic Neuropathy) 02/2018 - 03/2014
3	Chronic Pain 02/2018 - 01/2012
3	Edema (Dropsy) 01/2017 - 01/2013
3	Ischemia 12/2015 - 06/2014
2	Nervous System Diseases (Neurological Disorders) 10/2021 - 01/2018
2	Hepatocellular Carcinoma (Hepatoma) 01/2018 - 03/2014
2	Peritonitis 01/2017 - 06/2015
1	Acute Coronary Syndrome 10/2021
1	Fibrosis (Cirrhosis) 01/2019
1	Hyperglycemia 01/2019
1	Hypertrophy 01/2019
1	Insulin Resistance 01/2019
1	Hypertriglyceridemia 01/2019
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2019
1	Memory Disorders (Memory Loss) 01/2018
1	Neuroblastoma 01/2018
1	Major Depressive Disorder (Major Depressive Disorders) 04/2016
1	Orthostatic Hypotension (Postural Hypotension) 01/2016

Drug/Important Bio-Agent (IBA)

17	Formaldehyde (Formol)FDA Link 10/2021 - 01/2012
15	Epinephrine (Adrenaline)FDA LinkGeneric 01/2016 - 12/2004
14	Anticonvulsants (Antiepileptic Drugs)IBA 10/2021 - 01/2012
11	Analgesics (Analgesic Drugs)IBA 02/2020 - 09/2009
10	Pentylenetetrazole (Metrazol)IBA 01/2018 - 08/2014
7	Oxaliplatin (Eloxatin)FDA LinkGeneric 02/2020 - 07/2014
5	Pharmaceutical PreparationsIBA 11/2020 - 03/2014
5	Capsaicin (Zostrix)FDA Link 11/2020 - 09/2009
5	CarrageenanIBA 01/2020 - 01/2013
4	barium chloride (barium dichloride)IBA 01/2016 - 12/2004
3	Streptozocin (Streptozotocin)FDA Link 11/2020 - 06/2013
3	pyrrolidine-2,5-dioneIBA 02/2020 - 03/2016
3	Pregabalin (Lyrica)FDA Link 02/2020 - 07/2014
2	GABA Plasma Membrane Transport ProteinsIBA 10/2021 - 06/2015
2	LigandsIBA 01/2019 - 05/2015
2	SaltsIBA 01/2019 - 03/2015
2	Prazosin (Minipress)FDA LinkGeneric 01/2019 - 01/2019
2	MH-76 compoundIBA 01/2019 - 01/2019
2	MH-79 compoundIBA 01/2019 - 01/2019
2	AntioxidantsIBA 01/2019 - 03/2014
2	QuinazolinesIBA 01/2019 - 01/2019
2	Hypnotics and Sedatives (Sedatives)IBA 01/2018 - 06/2015
2	ZymosanIBA 01/2017 - 06/2015
2	AmidesIBA 06/2016 - 06/2016
2	gamma-Aminobutyric Acid (GABA)IBA 04/2016 - 01/2012
2	Pilocarpine (Ocusert)FDA LinkGeneric 03/2016 - 06/2015
2	Thioctic Acid (Lipoic Acid)IBA 01/2016 - 06/2014
2	XanthonesIBA 12/2015 - 01/2013
2	xanthoneIBA 12/2015 - 09/2014
2	Adrenergic Receptors (Adrenergic Receptor)IBA 10/2015 - 01/2013
2	Glutamic Acid (Glutamate)FDA Link 06/2015 - 09/2009
2	Tiagabine (Gabitril)FDA Link 06/2015 - 01/2012
2	Paclitaxel (Taxol)FDA LinkGeneric 03/2015 - 07/2014
2	2,3,4-tri-O-acetylarabinopyranosyl isothiocyanate (AITC)IBA 03/2015 - 07/2014
2	Adenosine Triphosphate (ATP)IBA 06/2014 - 01/2013
2	Acetic Acid (Vinegar)FDA LinkGeneric 09/2013 - 01/2012
2	phenylpiperazineIBA 04/2012 - 01/2011
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 10/2021
1	pyridineIBA 01/2020
1	Desoxycorticosterone Acetate (DOCA)FDA Link 01/2019
1	imidazoleIBA 01/2019
1	Acetates (Acetic Acid Esters)FDA Link 01/2019
1	Antihypertensive Agents (Antihypertensives)IBA 01/2019
1	Desoxycorticosterone (Deoxycorticosterone)IBA 01/2019
1	FructoseIBA 01/2019
1	Guanosine Monophosphate (5' Guanylic Acid)IBA 01/2019
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019
1	Histamine H3 Receptors (Histamine H3 Receptor)IBA 01/2019
1	Therapeutic UsesIBA 01/2019
1	Drinking WaterIBA 01/2019
1	Scopolamine (Hyoscine)FDA Link 01/2018
1	Cytochrome P-450 CYP3AIBA 01/2018
1	Verapamil (Calan)FDA LinkGeneric 06/2017
1	CalciumIBA 06/2017
1	Sodium Channels (Sodium Channel)IBA 06/2017
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 06/2017
1	Histamine H4 ReceptorsIBA 01/2017
1	Cholinergic Agents (Cholinergics)IBA 12/2016
1	3- phenyl- 2,5- dioxo- pyrrolidine- 1- yl- acetic acidIBA 06/2016
1	Levetiracetam (Keppra)FDA LinkGeneric 06/2016
1	imidazolidine-2,4-dioneIBA 06/2016
1	Phenytoin (Dilantin)FDA LinkGeneric 06/2016
1	Cholinergic ReceptorsIBA 04/2016
1	Calcium Chloride (Calcium Chloride, Anhydrous)FDA LinkGeneric 01/2016
1	Carvedilol (Coreg)FDA LinkGeneric 01/2016
1	2- (1,3- dimethyl- 2,6- dioxo- 1,2,3,6- tetrahydro- 7H- purin- 7- yl)- N- (4- isopropylphenyl)acetamideIBA 03/2015
1	A 967079IBA 03/2015
1	Transient Receptor Potential ChannelsIBA 03/2015

Therapy/Procedure

6	Drug Therapy (Chemotherapy) 02/2020 - 07/2013
2	Intravenous Injections 10/2015 - 01/2013
2	Therapeutics 06/2015 - 07/2013